Resources
Below, we have listed some resources generated in the lab with links to the publications, the datasets (proteomics, RNA-seq, Cut&Run) and to a repository where you can order the cell lines. Please feel free to get in touch if you have any questions or would like further information.
Cell lines and datasets
*This is a work in progress, and will be updated regularly with new cell lines, links to datasets, and references.
All of our published (and many unpublished) SWI/SNF engineered cell lines have been submitted and can be obtained at CancerTools.org
PBRM1 (BAF180) knockouts in 1BR3-hTERT (immortalised human fibroblast cells).
Clones 3 and 5
Reference: Feng et al (2022) Genes Dev 36:790-806
RNA-seq from untreated and irradiated (48h, 2Gy) KO cells and isogenic parental cells: GSE183688
Whole proteome from untreated and irradiated (48h, 2Gy) KO cells and isogenic parental cells: PXD028366
SMARCA4 (BRG1) knockout in HCT116 cell line.
Clone 2
Reference: Schiavoni et al (2022) Nat Comms 13:1371
Whole proteome from KO and isogenic parental cells cultured for short (<1month), medium (4 months) or long (8 months timeframes: PDX014954